Sample 60

Evaluation Instructions

Important: Models were tasked with extracting evidence from documents. Some outputs may be low quality and should be scored accordingly.

Your task: Compare the model-generated prediction (right panel) against the ground truth criteria (left panel).

Evaluation scale (0-4):

Consider both content accuracy and completeness. Some predictions may be technically "correct" but incomplete or out of order.

Ground Truth

INCLUSION CRITERIA

  1. Male and female outpatients 18 to 65 years of age, inclusive, at the time of informed consent.
  2. Participants who have PTSD, diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5), and confirmed by the Mini International Neuropsychiatric Interview (MINI).
  3. Onset of symptoms meeting the DSM-5 criteria for PTSD symptoms for a minimum of 6 months prior to screening.

EXCLUSION CRITERIA

  1. The index traumatic event that led to the develop of PTSD took place > 9 years before screening.
  2. The index traumatic event occurred before age 16.
  3. Participants who have experienced a traumatic event within 3 months of screening.
  4. Participants who are receiving disability payments because of PTSD or any other psychiatric disorder; unless the disability payments will not be impacted by potential improvements demonstrated in the trial.

Prediction

331-201-00071 31 Confidential - Proprietary Information Amendment 4 Approval: 04 Jan 2023 20. Subjects who have a history of alcohol or substance abuse (binge drinking or other substance abuse) that is currently active or that would be expected to abate within 3 months prior to the screening visit. 20.1.1 Note: The use of alcohol or other substances is strictly prohibited in the IMP. 21. Subjects who have a history of abuse of controlled substances (other than alcohol) that is currently active or that would be expected to abate within 3 months prior to the screening visit. 21.1.1 Note: The use of controlled substances other than alcohol is strictly prohibited in the IMP. 22. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 23. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 24. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 25. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 26. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 27. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 28. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 29. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 30. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 31. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 32. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 33. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 34. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 35. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 36. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 37. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 38. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 39. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 40. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 32 Protocol 331-201-00071 32 Confidential - Proprietary Information Amendment 4 Approval: 04 Jan 2023 41. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 42. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 43. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 44. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 45. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 46. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 47. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 48. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 49. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 50. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 51. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 52. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 53. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 54. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 55. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 56. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 57. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 58. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 59. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 60. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 61. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 62. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 63. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 64. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 65. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 66. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 67. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 68. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 69. Subjects who have a history of abuse of alcohol or other substances that is currently active or that would be expected to abate within 3 months prior to the screening visit. 70. Subjects who have a history of abuse of alcohol