Raw Ground Truth
Key Inclusion Criteria:Aged 12 to <18 yearsParent or legal guardian must provide written informed consentTreatment naïve or experienced children with genotype 1 or 4 HCV infection, and are on a maintenance cancer chemotherapy regimenReceiving a protocol-approved maintenance chemotherapy regimen for a hematological malignancyChronic HCV infection (≥ 6 months) documented by medical history or liver biopsyScreening laboratory values within defined thresholdsNo History of solid organ or bone marrow transplantationNo history of clinical hepatic decompensation (eg, ascites, jaundice, encephalopathy, variceal hemorrhage)NOTE: Other protocol defined Inclusion/ Exclusion criteria may apply.
Raw Prediction
Inclusion Criteria:
- Aged 12 to <18 years
- Parent or legal guardian must provide written informed consent
- Treatment naïve or experienced children with genotype 1 or 4 HCV infection, and are on a maintenance cancer chemotherapy regimen
- Receiving a protocol-approved maintenance chemotherapy regimen for a hematological malignancy
- Chronic HCV infection (≥ 6 months) documented by medical history or liver biopsy
- Screening laboratory values within defined thresholds
- No history of solid organ or bone marrow transplantation
- No history of clinical hepatic decompensation (e.g., ascites, jaundice, encephalopathy, variceal hemorrhage)
- Must have an absolute lymphocyte count ≥ 300/mm3
- Must not have any Grade 3 or greater rash associated with constitutional symptoms
- Must not have any Grade 4 adverse event or laboratory abnormality assessed as related to the investigational drug
Processed Ground Truth
1. Key Inclusion Criteria:Aged 12 to <18 yearsParent or legal guardian must provide written informed consentTreatment naïve or experienced children with genotype 1 or 4 HCV infection, and are on a maintenance cancer chemotherapy regimenReceiving a protocol-approved maintenance chemotherapy regimen for a hematological malignancyChronic HCV infection (≥ 6 months) documented by medical history or liver biopsyScreening laboratory values within defined thresholdsNo History of solid organ or bone marrow transplantationNo history of clinical hepatic decompensation (eg, ascites, jaundice, encephalopathy, variceal hemorrhage)NOTE: Other protocol defined Inclusion/ Exclusion criteria may apply.
Processed Prediction
1. Aged 12 to <18 years
2. Parent or legal guardian must provide written informed consent
3. Treatment naïve or experienced children with genotype 1 or 4 HCV infection, and are on a maintenance cancer chemotherapy regimen
4. Receiving a protocol-approved maintenance chemotherapy regimen for a hematological malignancy
5. Chronic HCV infection (≥ 6 months) documented by medical history or liver biopsy
6. Screening laboratory values within defined thresholds
7. No history of solid organ or bone marrow transplantation
8. No history of clinical hepatic decompensation (e.g., ascites, jaundice, encephalopathy, variceal hemorrhage)
9. Must have an absolute lymphocyte count ≥ 300/mm3
10. Must not have any Grade 3 or greater rash associated with constitutional symptoms
11. Must not have any Grade 4 adverse event or laboratory abnormality assessed as related to the investigational drug